The only real difference is the data you store in your local OneDrive folder is also stored on OneDrive servers. Using it is really little different from using any folder on your Mac. With that out of the way, is using Mac OneDrive easy and convenient? Yes. But OneDrive is proof that the needs of both their customers outweighs anything else. The rivalry between the two companies makes it seem unlikely they would shake hands and develop apps that complement both their individual operating systems. It's always such a pleasant surprise when applications developed by Microsoft end up with Apple. Click to know Which Files or Folders to Should Be Sync in OneDrive.